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Diabetic Retinopathy 

 

Introduction to Diabetic Retinopathy

Diabetic retinopathy is one of the complications, which arises due to ‘long-term diabetes’. It causes damage to the blood vessels of light sensitive tissue behind the retina of the eye. Initially, diabetic retinopathy shows no symptoms apart from mild vision problems, but gradually can lead to blindness. Diabetic retinopathy affects people suffering from type 1 or type 2 diabetes.

Epidemiology of Diabetic Retinopathy
World Health Organization estimates that 150 million people suffer from diabetes, worldwide and also suggests that the number will be doubled by the year 2025.1 Diabetic retinopathy is not seen in the initial 3–5 years after being diagnosed with type 1 diabetes. Other studies indicate that nearly 97.5% of patients with type 1 diabetes will have retinopathy after 15 years.2 With better diet control and bringing about a modification in the risk factors, diabetic retinopathy can be less threatening as predicted earlier.3 In children with diabetes, retinopathy is usually not seen before puberty.4

Classification of Diabetic Retinopathy

Diabetic retinopathy can be classified as:

  • Nonproliferative diabetic retinopathy–Nonproliferative diabetic retinopathy can be mild, moderate or severe.6 In this condition, the blood vessels of the retina weaken. As the condition advances large retinal veins begin to dilate. The nerve fibers of the retina also swell.
  • Proliferative diabetic retinopathy–In this condition abnormal blood vessels or a new blood vessels grow or leak a jelly-like substance, which fills the center of the eye. This gradually causes the formation of a scar tissue, which causes the retina to detach from behind the eye. This interferes in the normal blood flow and damages the optic nerve.

Treatment of Diabetic Retinopathy

Treatment of Diabetic Retinopathy


Written by: Healthplus24 team
Date last updated: July 18, 2011

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References 

 

  1. King H, Aubert RE, Herman WH. Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. Diabes Care. 1998; 21: 1414–1431.
  2. Klein R, Klein BE, Moss SE, et al.The Wisconsin epidemiologic study of diabetic retinopathy, II: prevalence and risk of diabetic retinopathy when age at diagnosis is less than 30 years. Arch Ophthalmol. 1984; 102: 520–526.
  3. Henricsson M, Nystrom L, Blohme G, et al. The incidence of retinopathy 10 years after diagnosis in young adult people with diabetes: results from the nationwide population-based Diabetes Incidence Study in Sweden (DISS). Diabetes Care. 2003; 26: 349–354.
  4. Jackson RL, Ide CH, Guthrie RA, et al.Retinopathy in adolescents and young adults with onset of insulin-dependent diabetes in childhood. Ophthalmology. 1982; 89: 7–13.
  5. Yoshida Y, Hagura R, Hara Y, et al. Risk factors for the development of diabetic retinopathy in Japanese type 2 diabetic patients. Diabetes Res Clin Prac. 2001; 51: 195–203.
  6. Early Treatment Diabetic Retinopathy Study Research Group. Early photocoagulation for diabetic retinopathy. ETDRS Report 9. Ophthalmology. 1991; 98: 766–785.
  7. Patel JI, Jykin PG, Schadt M. Pars plana vitrectomy with and without peeling of the internal limiting membrane for diabetic macular edema. Retina. 2006; 26: 5–13.
  8. The UK Prospective Diabetes Study Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet. 1998; 352: 837–853.
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